ISAAC

Iron Man #55"Beware - Beware - Beware the Blood Brothers!"

First appearance of Thanos. Earliest catalogued appearances of Drax the Destroyer, Starfox, Mentor, and 3 more.

Feb 1973

No listings

Captain Marvel #27"Trapped on Titan"

Jul 1973

No listings

Captain Marvel #31"The Beginning of the End"

Mar 1974

No listings

Captain Marvel #32"Thanos the Insane God"

May 1974

No listings

Captain Marvel #33"The God Himself!"

Jul 1974

No listings

Captain Marvel #58"A Destroyer -- Denied!"

Sep 1978

No listings

Captain Marvel #59"The Trouble with Titan"

Earliest catalogued appearance of Elysius.

Nov 1978

No listings

Captain Marvel #60"Moon-Traps and Paradise"

Jan 1979

No listings

Captain Marvel #61"Chaos and the Pit!"

Mar 1979

No listings

Captain Marvel #62"Earth Skirmish"

May 1979

No listings

Marvel Spotlight #1"The Saturn Storm!"

Jul 1979

No listings

Marvel Spotlight #2"The Dark Corners!"

Sep 1979

No listings

Marvel Spotlight #3"BLUE--RED--BLUE!"

Nov 1979

No listings

The Defenders #101

Nov 1981

No listings

Marvel Graphic Novel #1"The Death of Captain Marvel"

Earliest catalogued appearance of Shatterax.

Apr 1982

No listings

The Avengers #230"The Last Farewell"

Apr 1983

No listings

The Avengers #238"Unlimited Vision!"

Dec 1983

No listings

The Avengers #243"Chain of Command"

May 1984

No listings

Hercules #3"Deadly Legacy"

May 1984

No listings

The Avengers #249"The Snows of Summer"

Nov 1984

No listings

The Avengers Annual #13

Nov 1984

No listings

The Avengers #251"Deceptions!"

Jan 1985

No listings

Solo Avengers #16

Earliest catalogued appearance of MODAM.

Mar 1989

No listings

Solo Avengers #18

May 1989

No listings

Solo Avengers #20

Jul 1989

No listings

What If...? #19

Nov 1990

No listings

The Infinity Gauntlet #1"God"

Jul 1991

No listings

The Infinity Gauntlet #2"From Bad to Worse"

Earliest catalogued appearance of Epoch (Marvel).

Aug 1991

No listings

Silver Surfer #52

Aug 1991

No listings

Silver Surfer Annual #6

Earliest catalogued appearance of Genis-Vell.

Sep 1993

No listings

Quasar #59

Jun 1994

No listings

Cosmic Powers #4

Jun 1994

No listings

Code of Honor #4

May 1997

No listings

Ka-Zar #10

Feb 1998

No listings

Thunderbolts #46

Jan 2001

No listings

Thunderbolts #47

Feb 2001

No listings

Avengers: Celestial Quest #4

Feb 2002

No listings

She-Hulk #6"Beaus & Eros, Part 1: I'm With Cupid"

May 2006

No listings

She-Hulk #7"Beaus & Eros, Part 2: Change of Heart"

Jun 2006

No listings

She-Hulk #12"Remember The Titans"

Nov 2006

No listings

She-Hulk #13"Mind Field"

Dec 2006

No listings

Guardians of the Galaxy #9"Prison Break"

Mar 2009

No listings

Avengers Assemble #1

Jul 2010

No listings

The Thanos Imperative #3

Oct 2010

No listings