The twins, Yamato and Takeru Sannou, come to live with Yuri in her home. They are the 33rd reincarnation of Susanoo...!! The eight-headed serpent, Yamata no Orochi, has returned after 2,000 years and is targeting Yuri, the reincarnation of Kushinada-hime!
(Source: Akita Shoten, translated)
— Description from AniList community (anilist.co).
