The Fantastic Four invade the 1999 San Diego Comic Con! Racing against the clock, the FF must find a cure for the nanite infection that has attacked the Thing and guest-star She-Hulk?which leads them to... a comic book convention?! Plus: The Red Skull, the Mad Thinker and his awesome android! And finally, just who is Valeria Von Doom?!"
— Description from Comic Vine community (comicvine.gamespot.com).
