Ben, Sue, and Johnny find themselves in a rescue mission in Genosha, trying to extricate Reed, in the midst of civil war. Following the events of the previous issue, they have to adjust to their new bodies first. While Reed Richards realises what he had feared for a while, he has been operating with diminished intellect since a previous battle with Crucible. While he retains a perfect memory, and can recreate anything he has built before, he is unable to construct anything new. Meanwhile, they must face Crucible one more time. Can Mr Fantastic figure a way out?
— Description from Comic Vine community (comicvine.gamespot.com).
