Mad scientist Desty Nova resurrects the brain of Zapan - the Hunter-Warrior whose pride Alita has injured one too many times - and grafts it with a deadly Berserker body. Now, nothing can stop Zapan from exacting his revenge on Alita and all the Scrapyard inhabitants. Will Alita sacrifice herself to save her friends and other innocents?
— Description from Comic Vine community (comicvine.gamespot.com).