There's magic and mayhem in the air as Deadpool signs up to help Doctor Druid's secret Defenders stop the mystical malefactress Malachi from unleashing mayhem! Next, Black Tom Cassidy's in a bad way and the only thing that can help him is Wade's regeneratin' genetic matter. Luckily, the Merc with a Mouth has got Sean and Theresa Cassidy, aka the sonically skilled mutants Banshee and Siryn in his corner - and with the unstoppable Juggernaut leading the hunt, he's going to need all the help he can get! Finally, we bring you a landmark moment in the history of Wade Wilson as we present a first-ever showdown with fellow Weapon X outcast Wolverine!
