Ch. 1 cliffhanger ending - Larry Grayson's friend, Dwight, is given a potion by an evil witch doctor that turns him into a human jaguar. Shortly thereafter Dwight attacks Nyoka and the jungle girl has no idea why Dwight is attacking her.
Ch. 2 cliffhanger ending - The tribal witch doctor knocks Nyoka out. He binds her arms so she can't escape. Then he grabs her head with one hand and in the other hand he puts a cup filled with the deadly potion up to her mouth, as he plans to transform Nyoka into a human jaguar girl!
— Description from Comic Vine community (comicvine.gamespot.com).
